Generate Postback with isPostback C# ASPX

page.aspx

<script type="text/javascript">
$(function () {
     //javascript or jQuery event
     $("#MyButton").click(function() {
          <%=PostBackString %> //this will insert our postback code at runtime
     });
});
</script>

page.aspx.cs

protected string PostBackString;
protected void Page_Load(object sender, EventArgs e)
{
     //this gets the postback code that we will use on our aspx page
     PostBackString = Page.ClientScript.GetPostBackEventReference(this, "MyEventArgumentName");
     if (IsPostBack) 
     {
          //Check if the postback was caused by our event
          if (Request["__EVENTARGUMENT"] == "MyEventArgumentName")
          {
               //Do something
          }
     }
}